it is all over with smb.

it is all over with smb.
(it is all over (all up, жарг. all UP или U. P.) with smb.)
≈ его (её и т. д.) песенка спета, с ним (с ней и т. д.) всё кончено, он (она и т. д.) человек конченый, ему (ей и т. д.) конец, крышка

‘Oh!’ said the young man, turning his face towards the bed as if he had previously quite forgotten the patient, ‘it's all U. P. there, Mrs Corney.’ (Ch. Dickens, ‘Oliver Twist’, ch. XXIV) — - О! - сказал молодой человек, поворачиваясь к кровати с таким видом, будто совсем забыл о пациентке. - Ее песенка спета, миссис Корни.

But if it comes to a gunfight that means it's all up with at least one of us. Delaney never misses his man. (Fr. Norris, ‘The Octopus’, book II, ch. VI) — Но если дело дойдет до стрельбы, то кому-то из нас несдобровать. Делани не даст промаха.

The daylight was a comfort, but a danger as well, for they might be seen by a German motor boat and then it was all up with them. (W. S. Maugham, ‘The Hour before the Dawn’, ch. XIII) — Рассвет принесет им облегчение, но ведь он таит в себе и опасность: их может заметить немецкий моторный катер и тогда пиши пропало.


Большой англо-русский фразеологический словарь. - М.: «Русский язык-Медиа».. 2006.

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